Drug Shortages Epidemic In Anesthesiology

anesthesia 3

There is no end in sight to the now business as usual reality of drug shortages in medicine. Anesthesiology is hit particularly hard in the number of medications which are not being manufactured to meet demand. Here is a list of medications common to anesthesia practice which the FDA lists as being in short supply, and the reasons given. It contains the three most frequently administered medications in the practice of anesthesia: propofol, fentanyl and midazolam. Law Med points out that it is no coincidence that only drugs which are off patent and now generics seem to have shortages.

Alfentanil Injection  Material shortage and increased demand.

Atracurium besylate   Manufacturing delays.

Atropine Sulfate Injection  Manufacturing delay and increased demand.

Bupivacaine Hydrochloride Injection   Manufacturing delay.

Calcium Chloride Injection  Manufacturing delay.

Chloroprocaine (Nesacaine) Injection  Increased demand and manufacturing delay.

Etomidate Injection  increased demand and manufacturing delay.

Fentanyl Citrate Injection Manufacturing delay causing increased demand.

Hydromorphone Hydrochloride Injection   Material shortage, manufacturing delay, increased demand 

Ketorolac Injection  Manufacturing delay, material shortage, increased demand. 

Lidocaine Hydrochloride Injection   Manufacturing delay.

Lorazepam Injection  Manufacturing delay, production discontinued, increased demand. 

Metoclopramide Injection  manufacturer delay.

Midazolam Injection  Temporary suspension of manufacturing, Other manufacturer shortage/withdrawal; Manufacturing delay; Quality improvement activities.

Morphine Sulfate Injection  Manufacturing delay.

Morphine Sulfate Injection (Preservative Free)  Manufacturer delay.

Naloxone Injection  Manufacturer delay causing increased demand.

Ondansetron Injection 2 mg/mL  Temporary discontine manufacturinsg, discontinue manufacturing, increased demand.

Pancuronium Bromide Injection  Manufacturing delay.

Propofol Injection  Manufacturing delay and increased demand. 

Sodium Bicarbonate Injection  Manufacturing delay causing increased demand. 

Sufentanil Injection  Materials delay, manufacturing delay.

Vecuronium Injection  Manufacturing delay, increased demand. 

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One Response to Drug Shortages Epidemic In Anesthesiology

  1. TonyFrancis says:

    There seems to be a concerted effort to get rid of all drugs that can’t be marketed leading to a significant charge. It is occurring in a lot of ways. For instance demanding extensive trials for drugs, or they will be pulled off the market. Two examples are colchicine and propoxyphene.

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